Mostacci, Barbara ; Ferlisi, Monica ; Baldi Antognini, Alessandro ; Sama, Claudia ; Morelli, Cristina ; Mondini, Susanna ; Cirignotta, Fabio
(2008)
Sleep Disturbance and Daytime Sleepiness in Patients with Cirrhosis: a Case Control Study.
[Preprint]
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Abstract
Objective: Sleep disturbance and excessive daytime sleepiness have been reported in patients
with hepatic cirrhosis. The objective of this study was to evaluate daytime somnolence and
sleep complaints in a group of 178 patients with cirrhosis compared to a control group.
Method: Sleep features and excessive daytime sleepiness were evaluated by the Basic Nordic
Sleep Questionnaire (BNSQ) and the Epworth Sleepiness Scale (ESS). We collected clinical
and laboratory data, neurological assessment and EEG recording in cirrhotic patients.
Results: Patients with cirrhosis complained of more daytime sleepiness (p<0.005), sleeping
badly at least three times a week (p<0.005), difficulties falling asleep (p<0.01) and frequent
nocturnal awakening (p<0.005) than controls. We found a poor correlation between sleep
disorders and clinical or laboratory parameters. Conclusion: Our results confirm previous
literature reports suggesting a high prevalence of sleep disturbance in patients with cirrhosis.
Insomnia and daytime sleepiness are the main complaints. Sleep disorders are probably a
multifactorial phenomenon.
Abstract
Objective: Sleep disturbance and excessive daytime sleepiness have been reported in patients
with hepatic cirrhosis. The objective of this study was to evaluate daytime somnolence and
sleep complaints in a group of 178 patients with cirrhosis compared to a control group.
Method: Sleep features and excessive daytime sleepiness were evaluated by the Basic Nordic
Sleep Questionnaire (BNSQ) and the Epworth Sleepiness Scale (ESS). We collected clinical
and laboratory data, neurological assessment and EEG recording in cirrhotic patients.
Results: Patients with cirrhosis complained of more daytime sleepiness (p<0.005), sleeping
badly at least three times a week (p<0.005), difficulties falling asleep (p<0.01) and frequent
nocturnal awakening (p<0.005) than controls. We found a poor correlation between sleep
disorders and clinical or laboratory parameters. Conclusion: Our results confirm previous
literature reports suggesting a high prevalence of sleep disturbance in patients with cirrhosis.
Insomnia and daytime sleepiness are the main complaints. Sleep disorders are probably a
multifactorial phenomenon.
Document type
Preprint
Creators
Keywords
liver cirrhosis, insomnia, daytime somnolence
Subjects
DOI
Deposit date
20 Jun 2008
Last modified
16 May 2011 12:08
URI
Other metadata
Document type
Preprint
Creators
Keywords
liver cirrhosis, insomnia, daytime somnolence
Subjects
DOI
Deposit date
20 Jun 2008
Last modified
16 May 2011 12:08
URI
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