Sleep Disturbance and Daytime Sleepiness in Patients with Cirrhosis: a Case Control Study

Mostacci, Barbara ; Ferlisi, Monica ; Baldi Antognini, Alessandro ; Sama, Claudia ; Morelli, Cristina ; Mondini, Susanna ; Cirignotta, Fabio (2008) Sleep Disturbance and Daytime Sleepiness in Patients with Cirrhosis: a Case Control Study. [Preprint]
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Abstract

Objective: Sleep disturbance and excessive daytime sleepiness have been reported in patients with hepatic cirrhosis. The objective of this study was to evaluate daytime somnolence and sleep complaints in a group of 178 patients with cirrhosis compared to a control group. Method: Sleep features and excessive daytime sleepiness were evaluated by the Basic Nordic Sleep Questionnaire (BNSQ) and the Epworth Sleepiness Scale (ESS). We collected clinical and laboratory data, neurological assessment and EEG recording in cirrhotic patients. Results: Patients with cirrhosis complained of more daytime sleepiness (p<0.005), sleeping badly at least three times a week (p<0.005), difficulties falling asleep (p<0.01) and frequent nocturnal awakening (p<0.005) than controls. We found a poor correlation between sleep disorders and clinical or laboratory parameters. Conclusion: Our results confirm previous literature reports suggesting a high prevalence of sleep disturbance in patients with cirrhosis. Insomnia and daytime sleepiness are the main complaints. Sleep disorders are probably a multifactorial phenomenon.

Abstract
Document type
Preprint
Creators
CreatorsAffiliationORCID
Mostacci, Barbara
Ferlisi, Monica
Baldi Antognini, Alessandro
Sama, Claudia
Morelli, Cristina
Mondini, Susanna
Cirignotta, Fabio
Keywords
liver cirrhosis, insomnia, daytime somnolence
Subjects
DOI
Deposit date
20 Jun 2008
Last modified
16 May 2011 12:08
URI

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