Abstract

This dataset supports a clinical audit evaluating antimicrobial stewardship program (ASPs) in a Veterinary Teaching Hospital, focusing on antimicrobial-resistant bacteria (AMRb) colonization rates (CR) in horses under the One Health approach. Nasal and rectal swabs from 328 hospitalized horses (foals and adults) across two audit cycles: - A1 (Jan-Jul 2022); - A2 (Jan-Jul 2023): after ASP implementation about antimicrobial use (AMU) and biosecurity policy. Swabs were collected at admission/birth (T0) and discharge/euthanasia/death (T1); tested for Methicillin-resistant Staphylococci (MRS), 3rd-generation Cephalosporin-resistant Gram-Negative Bacteria (3GCR-GNB), and Carbapenem-resistant Gram-Negative Bacteria (CR-GNB).