Neuroactive Steroids in First-Episode Psychosis: A Role for Progesterone?

Belvederi Murri, Martino ; Fanelli, Flaminia ; Pagotto, Uberto ; Bonora, Elena ; Triolo, Federico ; Chiri, Luigi ; Allegri, Fabio ; Mezzullo, Marco ; Menchetti, Marco ; Mondelli, Valeria ; Pariante, Carmine ; Berardi, Domenico ; Tarricone, Ilaria (2016) Neuroactive Steroids in First-Episode Psychosis: A Role for Progesterone? Schizophrenia Research and Treatment, 2016 . ISSN 2090-2093

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URL ufficiale: https://www.hindawi.com/journals/schizort/2016/1942828/

Abstract

Neuroactive steroids may play a role in the pathophysiology of psychotic disorders, but few studies examined this issue. We compared serumlevels of cortisol, testosterone, dehydroepiandrosterone, and progesterone between a representative sample of firstepisode psychosis (FEP) patients and age- and gender-matched healthy subjects. Furthermore, we analyzed the associations between neuroactive steroids levels and the severity of psychotic symptom dimensions.Male patients had lower levels of progesterone than controls (

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Autore	Affiliazione	ORCID
Belvederi Murri, Martino
Fanelli, Flaminia
Pagotto, Uberto
Bonora, Elena
Triolo, Federico
Chiri, Luigi
Allegri, Fabio
Mezzullo, Marco
Menchetti, Marco
Mondelli, Valeria
Pariante, Carmine
Berardi, Domenico
Tarricone, Ilaria	Department of Medical and Surgical Sciences	orcid.org/0000-0002-5786-2520