Data from molecular mechanism investigation on new purposely designed hybrid compounds to inhibit NDH-2 enzyme of P. falciparum and S. aureus

Bisi, Alessandra ; Bonvicini, Francesca (2024) Data from molecular mechanism investigation on new purposely designed hybrid compounds to inhibit NDH-2 enzyme of P. falciparum and S. aureus. University of Bologna. DOI 10.6092/unibo/amsacta/8071. [Dataset]
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Abstract

A series of hybrid compounds has been designed and synthesized by linking the pharmacophore of the antimalarial drug chloroquine with the phenothiazine core. The dataset contains the free induction decay (fid) of 1H and 13C NMR spectra registered on a Bruker spectrometer working at 600 MHz and at 150 MHz of the new compounds and the optical density measurements of the microbial and cellular growths of the experimental model systems treated with the hybrid compounds.

Abstract
Tipologia del documento
Dataset
Autori
AutoreORCIDAffiliazioneROR
Bisi, Alessandra0000-0003-4662-4743University of Bologna, Department of Pharmacy and Biotechnology - FaBit
Bonvicini, Francesca0000-0001-8101-9835University of Bologna, Department of Pharmacy and Biotechnology - FaBit
Settori scientifico-disciplinari
Area 03 - Scienze chimiche > CHIM/08 Chimica farmaceutica
Area 06 - Scienze mediche > MED/07 Microbiologia e microbiologia clinica
DOI
10.6092/unibo/amsacta/8071
Contributors
Contributor
ORCID
Tipo
Affiliazione
Belluti, Federica
Data curator
University of Bologna, Department of Pharmacy and Biotechnology - FaBit
Gobbi, Silvia
Data curator
University of Bologna, Department of Pharmacy and Biotechnology - FaBit
Gentilomi, Giovanna Angela
Data curator
University of Bologna, Department of Pharmacy and Biotechnology - FaBitgie
Bisi, Alessandra
Contact person
University of Bologna, Department of Pharmacy and Biotechnology - FaBit
Bonvicini, Francesca
Contact person
University of Bologna, Department of Pharmacy and Biotechnology - FaBit
Data di deposito
09 Gen 2025 09:29
Ultima modifica
09 Gen 2025 09:29
URI
https://amsacta.unibo.it/id/eprint/8071

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© ALMA MATER STUDIORUM - Università d Bologna, 2007-2025.

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