Data from molecular mechanism investigation on new purposely designed hybrid compounds to inhibit NDH-2 enzyme of P. falciparum and S. aureus

Bisi, Alessandra ; Bonvicini, Francesca (2024) Data from molecular mechanism investigation on new purposely designed hybrid compounds to inhibit NDH-2 enzyme of P. falciparum and S. aureus. University of Bologna. DOI 10.6092/unibo/amsacta/8071. [Dataset]
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Abstract

A series of hybrid compounds has been designed and synthesized by linking the pharmacophore of the antimalarial drug chloroquine with the phenothiazine core. The dataset contains the free induction decay (fid) of 1H and 13C NMR spectra registered on a Bruker spectrometer working at 600 MHz and at 150 MHz of the new compounds and the optical density measurements of the microbial and cellular growths of the experimental model systems treated with the hybrid compounds.

Abstract
Tipologia del documento
Dataset
Autori
AutoreAffiliazioneORCID
Bisi, AlessandraUniversity of Bologna, Department of Pharmacy and Biotechnology - FaBit0000-0003-4662-4743
Bonvicini, FrancescaUniversity of Bologna, Department of Pharmacy and Biotechnology - FaBit0000-0001-8101-9835
Settori scientifico-disciplinari
Area 03 - Scienze chimiche > CHIM/08 Chimica farmaceutica
Area 06 - Scienze mediche > MED/07 Microbiologia e microbiologia clinica
DOI
10.6092/unibo/amsacta/8071
Contributors
Contributor
Affiliazione
ORCID
Tipo
Belluti, Federica
University of Bologna, Department of Pharmacy and Biotechnology - FaBit
Data curator
Gobbi, Silvia
University of Bologna, Department of Pharmacy and Biotechnology - FaBit
Data curator
Gentilomi, Giovanna Angela
University of Bologna, Department of Pharmacy and Biotechnology - FaBitgie
Data curator
Bisi, Alessandra
University of Bologna, Department of Pharmacy and Biotechnology - FaBit
Contact person
Bonvicini, Francesca
University of Bologna, Department of Pharmacy and Biotechnology - FaBit
Contact person
Data di deposito
09 Gen 2025 09:29
Ultima modifica
09 Gen 2025 09:29
URI
https://amsacta.unibo.it/id/eprint/8071

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© ALMA MATER STUDIORUM - Università d Bologna, 2007-2025.

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