Bisi, Alessandra ; Bonvicini, Francesca
(2024)
Data from molecular mechanism investigation on new purposely designed hybrid compounds to inhibit NDH-2 enzyme of P. falciparum and S. aureus.
University of Bologna.
DOI 10.6092/unibo/amsacta/8071.
[Dataset]
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Archivio (NMR-fid)
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Foglio di Calcolo (Candida_OD_measurements)
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Foglio di Calcolo (Cell_Viability_OD_measurements)
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Foglio di Calcolo (Coli_OD_measurements)
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Foglio di Calcolo (Staf_OD_measurements)
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Documento di testo(rtf) (README file)
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Abstract
A series of hybrid compounds has been designed and synthesized by linking the pharmacophore of the antimalarial drug chloroquine with the phenothiazine core. The dataset contains the free induction decay (fid) of 1H and 13C NMR spectra registered on a Bruker spectrometer working at 600 MHz and at 150 MHz of the new compounds and the optical density measurements of the microbial and cellular growths of the experimental model systems treated with the hybrid compounds.
Abstract


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