Data from molecular mechanism investigation on new purposely designed hybrid compounds to inhibit NDH-2 enzyme of P. falciparum and S. aureus

Bisi, Alessandra ; Bonvicini, Francesca (2024) Data from molecular mechanism investigation on new purposely designed hybrid compounds to inhibit NDH-2 enzyme of P. falciparum and S. aureus. University of Bologna. DOI 10.6092/unibo/amsacta/8071. [Dataset]
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Abstract

A series of hybrid compounds has been designed and synthesized by linking the pharmacophore of the antimalarial drug chloroquine with the phenothiazine core. The dataset contains the free induction decay (fid) of 1H and 13C NMR spectra registered on a Bruker spectrometer working at 600 MHz and at 150 MHz of the new compounds and the optical density measurements of the microbial and cellular growths of the experimental model systems treated with the hybrid compounds.

Abstract
Document type
Dataset
Creators
CreatorsAffiliationORCID
Bisi, AlessandraUniversity of Bologna, Department of Pharmacy and Biotechnology - FaBit0000-0003-4662-4743
Bonvicini, FrancescaUniversity of Bologna, Department of Pharmacy and Biotechnology - FaBit0000-0001-8101-9835
Subjects
Area 03 - Scienze chimiche > CHIM/08 Chimica farmaceutica
Area 06 - Scienze mediche > MED/07 Microbiologia e microbiologia clinica
DOI
10.6092/unibo/amsacta/8071
Contributors
Name
Affiliation
ORCID
Type
Belluti, Federica
University of Bologna, Department of Pharmacy and Biotechnology - FaBit
Data Curator
Gobbi, Silvia
University of Bologna, Department of Pharmacy and Biotechnology - FaBit
Data Curator
Gentilomi, Giovanna Angela
University of Bologna, Department of Pharmacy and Biotechnology - FaBitgie
Data Curator
Bisi, Alessandra
University of Bologna, Department of Pharmacy and Biotechnology - FaBit
Contact person
Bonvicini, Francesca
University of Bologna, Department of Pharmacy and Biotechnology - FaBit
Contact person
Deposit date
09 Jan 2025 09:29
Last modified
09 Jan 2025 09:29
URI
https://amsacta.unibo.it/id/eprint/8071

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