Fracassa, Alessandro
(2025)
ECLIPSE. WP1 Task 1.1. Breakable Ru complex for enhanced bead-based ECL immunoassay.
University of Bologna.
DOI
10.6092/unibo/amsacta/8482.
[Dataset]
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Abstract
The present dataset continues a previously deposited dataset (https://doi.org/10.6092/unibo/amsacta/8318) as part of the ECLipse project, focusing on the electrochemiluminescence (ECL) behavior of magnetic microbeads functionalized with a stimuli-responsive derivative of [Ru(bpy)3]2+. The reduction-sensitive disulfide bridge, that links the luminophore to the bead, gets cleaved upon reaction with the neutral TPrA radical, releasing the luminophore in solution and activating the homogeneous mechanism. These microbeads were studied under a microscope on glassy carbon (GC) and Pt substrates at different concentrations of TPrA. Further experiments were conducted on bead-based immunoassays for SARS-CoV-2 detection.
Abstract
The present dataset continues a previously deposited dataset (https://doi.org/10.6092/unibo/amsacta/8318) as part of the ECLipse project, focusing on the electrochemiluminescence (ECL) behavior of magnetic microbeads functionalized with a stimuli-responsive derivative of [Ru(bpy)3]2+. The reduction-sensitive disulfide bridge, that links the luminophore to the bead, gets cleaved upon reaction with the neutral TPrA radical, releasing the luminophore in solution and activating the homogeneous mechanism. These microbeads were studied under a microscope on glassy carbon (GC) and Pt substrates at different concentrations of TPrA. Further experiments were conducted on bead-based immunoassays for SARS-CoV-2 detection.
Tipologia del documento
Dataset
Autori
Parole chiave
Sensor, Immunoassay, Covid 19
Settori scientifico-disciplinari
DOI
Contributors
Data di deposito
01 Set 2025 14:13
Ultima modifica
01 Set 2025 14:14
Risorse collegate
Nome del Progetto
Programma di finanziamento
EC - HE
URI
Altri metadati
Tipologia del documento
Dataset
Autori
Parole chiave
Sensor, Immunoassay, Covid 19
Settori scientifico-disciplinari
DOI
Contributors
Data di deposito
01 Set 2025 14:13
Ultima modifica
01 Set 2025 14:14
Risorse collegate
Nome del Progetto
Programma di finanziamento
EC - HE
URI
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