ECLIPSE. WP1 Task 1.1. Breakable Ru complex for enhanced bead-based ECL immunoassay

Fracassa, Alessandro (2025) ECLIPSE. WP1 Task 1.1. Breakable Ru complex for enhanced bead-based ECL immunoassay. University of Bologna. DOI 10.6092/unibo/amsacta/8482. [Dataset]
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Abstract

The present dataset continues a previously deposited dataset (https://doi.org/10.6092/unibo/amsacta/8318) as part of the ECLipse project, focusing on the electrochemiluminescence (ECL) behavior of magnetic microbeads functionalized with a stimuli-responsive derivative of [Ru(bpy)3]2+. The reduction-sensitive disulfide bridge, that links the luminophore to the bead, gets cleaved upon reaction with the neutral TPrA radical, releasing the luminophore in solution and activating the homogeneous mechanism. These microbeads were studied under a microscope on glassy carbon (GC) and Pt substrates at different concentrations of TPrA. Further experiments were conducted on bead-based immunoassays for SARS-CoV-2 detection.

Abstract
Tipologia del documento
Dataset
Autori
AutoreAffiliazioneORCID
Fracassa, AlessandroUniversity of Bologna0009-0005-2685-1748
Parole chiave
Sensor, Immunoassay, Covid 19
Settori scientifico-disciplinari
DOI
Contributors
Contributor
Affiliazione
ORCID
Tipo
Valenti, Giovanni
University of Bologna
Contact person
Prodi, Luca
University of Bologna
Project leader
Data di deposito
01 Set 2025 14:13
Ultima modifica
01 Set 2025 14:14
Risorse collegate
Tipologia
Relazione
Identificativo
DOI
questo contributo è una continuazione di
Nome del Progetto
ECLIPSE - ECL-based Infectious Pathogen (bio)SEnsor
Programma di finanziamento
EC - HE
URI

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