Quantitative data on immune cell infiltration (T lymphocytes, B lymphocytes, and macrophages) in canine soft tissue sarcomas.

Avallone, Giancarlo ; Brigandì, Elena ; Bacci, Barbara ; Rigillo, Antonella ; Roccabianca, Paola ; Tugnoli, Chiara (2026) Quantitative data on immune cell infiltration (T lymphocytes, B lymphocytes, and macrophages) in canine soft tissue sarcomas. University of Bologna. DOI 10.6092/unibo/amsacta/8731. [Dataset]
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Abstract

the dataset contains the quantitative data regarding immune cell infiltration in a case series of canine soft tissue sarcoma. Immune cells were quantified by immunohistochemistry followed by image analysis on digitalised sections. Markers used to detect immune cells were: CD20 (B cells), CD3 (T cells), FOXP3, (Treg cells), Iba-1 (macrophages), CD204 (M2-like macrophages). For each case the age, breed and sex of the affected animal were also collected. Histological variables included in the datasets are the specific diagnosis (sarcoma type), mitotic count, histological grade.

Abstract
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Creators
CreatorsORCIDAffiliationROR
Avallone, Giancarlo0000-0002-5203-7679University of Bologna, Department of Veterinary Medical Sciences – DIMEVET, Bologna, Italy
Brigandì, ElenaUniversity of Bologna, Department of Veterinary Medical Sciences – DIMEVET, Bologna, Italy
Bacci, Barbara0000-0002-2206-0384University of Bologna, Department of Veterinary Medical Sciences – DIMEVET, Bologna, Italy
Rigillo, Antonellai-vet
Roccabianca, Paola0000-0002-3672-4612Università Degli Studi di Milano, Department of Veterinary Medicine and Animal Scien-ces, Lodi, Italy
Tugnoli, ChiaraUniversity of Bologna, Department of Veterinary Medical Sciences – DIMEVET, Bologna, Italy
Keywords
canine sarcoma, tumor microenvironment, immune cells, tumor infiltrating lymphocytes, tumor associated macrophages
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Avallone, Giancarlo
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University of Bologna, Department of Veterinary Medical Sciences – DIMEVET, Bologna, Italy
Deposit date
16 Jan 2026 08:28
Last modified
16 Jan 2026 14:46
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