Abstract

This dataset contains data from the analysis of the metabolic flux control coefficient obtained by evaluating respiratory chain activity. NADH-O2 oxidoreductase activity related to Complex I and N,N,N′,N′ -tetramethyl-p-phenylenediamine dihydrochloride (TMPD)/Ascorbate-O2 activity (TMPD/ASC-O2 oxidoreductase activity) related to Complex IV of the electron transport chain were recorded by titrating with KCN, a known inhibitor of Complex IV. Another dataset was obtained under the same conditions with the addition of exogenous Cyt C. Furthermore, proteomic analysis of respiratory supercomplexes was performed to assess their integrity. For this study, cardiac mitochondria from spontaneously hypertensive rats (SHR), both stroke-resistant (SR) and stroke-prone (SP), were used, and all groups of animals were fed a normal diet (ND) or a Japanese diet (JD).