Neuroactive Steroids in First-Episode Psychosis: A Role for Progesterone?

Belvederi Murri, Martino ; Fanelli, Flaminia ; Pagotto, Uberto ; Bonora, Elena ; Triolo, Federico ; Chiri, Luigi ; Allegri, Fabio ; Mezzullo, Marco ; Menchetti, Marco ; Mondelli, Valeria ; Pariante, Carmine ; Berardi, Domenico ; Tarricone, Ilaria (2016) Neuroactive Steroids in First-Episode Psychosis: A Role for Progesterone? Schizophrenia Research and Treatment, 2016 . ISSN 2090-2093
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Abstract

Neuroactive steroids may play a role in the pathophysiology of psychotic disorders, but few studies examined this issue. We compared serumlevels of cortisol, testosterone, dehydroepiandrosterone, and progesterone between a representative sample of firstepisode psychosis (FEP) patients and age- and gender-matched healthy subjects. Furthermore, we analyzed the associations between neuroactive steroids levels and the severity of psychotic symptom dimensions.Male patients had lower levels of progesterone than controls (

Abstract
Document type
Article
Creators
CreatorsAffiliationORCID
Belvederi Murri, Martino
Fanelli, Flaminia
Pagotto, Uberto
Bonora, Elena
Triolo, Federico
Chiri, Luigi
Allegri, Fabio
Mezzullo, Marco
Menchetti, Marco
Mondelli, Valeria
Pariante, Carmine
Berardi, Domenico
Tarricone, IlariaDepartment of Medical and Surgical Sciencesorcid.org/0000-0002-5786-2520
Subjects
ISSN
2090-2093
DOI
Deposit date
12 Jan 2017 14:02
Last modified
08 May 2017 13:03
Project name
EU-GEI - European Network of National Schizophrenia Networks Studying Gene-Environment Interactions
Funding program
EC - FP7
URI

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